Docosahexaenoic acid in the treatment of rheumatoid arthritis: A double-blind, placebo-controlled, randomized cross-over study with microalgae vs. sunflower oil
2018-01-01 Dawczynski, C.; Dittrich, M.; Neumann, T.; Goetze, K.; Welzel, A.; Oelzner, P.; Volker, S.; Schaible, A. M.; Troisi, F.; Thomas, L.; Pace, S.; Koeberle, A.; Werz, O.; Schlattmann, P.; Lorkowski, S.; Jahreis, G.
5α-dihydrotestosterone abrogates sex bias in asthma like features in the mouse
2020-01-01 Cerqua, I.; Terlizzi, M.; Bilancia, R.; Riemma, M. A.; Citi, V.; Martelli, A.; Pace, S.; Spaziano, G.; D'Agostino, B.; Werz, O.; Ialenti, A.; Sorrentino, R.; Cirino, G.; Rossi, A.; Roviezzo, F.
Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
2020-01-01 Jordan, P. M.; Gerstmeier, J.; Pace, S.; Bilancia, R.; Rao, Z.; Borner, F.; Miek, L.; Gutierrez-Gutierrez, O.; Arakandy, V.; Rossi, A.; Ialenti, A.; Gonzalez-Estevez, C.; Loffler, B.; Tuchscherr, L.; Serhan, C. N.; Werz, O.
Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammation
2018-01-01 Bruno, F.; Errico, S.; Pace, S.; Nawrozkij, M. B.; Mkrtchyan, A. S.; Guida, F.; Maisto, R.; Olgac, A.; D'Amico, M.; Maione, S.; De Rosa, M.; Banoglu, E.; Werz, O.; Fiorentino, A.; Filosa, R.
In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis
2014-01-01 Rossi, A.; Pergola, C.; Pace, S.; Radmark, O.; Werz, O.; Sautebin, L.
Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders
2020-01-01 Brancaleone, V.; Dalli, J.; D'Emmanuele Di Villa Bianca, R.; Pace, S.
Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions
2017-01-01 Maione, F.; Cantone, V.; Pace, S.; Chini, M. G.; Bisio, A.; Romussi, G.; Pieretti, S.; Werz, O.; Koeberle, A.; Mascolo, N.; Bifulco, G.
Sex-biased eicosanoid biology: Impact for sex differences in inflammation and consequences for pharmacotherapy
2017-01-01 Pace, S.; Sautebin, L.; Werz, O.
Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes
2020-01-01 Rao, Z.; Jordan, P. M.; Wang, Y.; Menche, D.; Pace, S.; Gerstmeier, J.; Werz, O.
Impact of Androgens on Inflammation-Related Lipid Mediator Biosynthesis in Innate Immune Cells
2020-01-01 Pace, S.; Werz, O.
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold
2019-01-01 Reale, A.; Brogi, S.; Chelini, A.; Paolino, M.; Di Capua, A.; Giuliani, G.; Cappelli, A.; Giorgi, G.; Chemi, G.; Grillo, A.; Valoti, M.; Sautebin, L.; Rossi, A.; Pace, S.; La Motta, C.; Di Cesare Mannelli, L.; Lucarini, E.; Ghelardini, C.; Anzini, M.
Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation
2017-01-01 Schieferdecker, S.; Konig, S.; Pace, S.; Werz, O.; Nett, M.
Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy
2017-01-01 Pergola, C.; Schubert, K.; Pace, S.; Ziereisen, J.; Nikels, F.; Scherer, O.; Huttel, S.; Zahler, S.; Vollmar, A. M.; Weinigel, C.; Rummler, S.; Muller, R.; Raasch, M.; Mosig, A.; Koeberle, A.; Werz, O.
Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy
2019-01-01 Gerstmeier, J.; Kretzer, C.; Di Micco, S.; Miek, L.; Butschek, H.; Cantone, V.; Bilancia, R.; Rizza, R.; Troisi, F.; Cardullo, N.; Tringali, C.; Ialenti, A.; Rossi, A.; Bifulco, G.; Werz, O.; Pace, S.
The anti-inflammatory and antimicrobial potential of selected ethnomedicinal plants from Sri Lanka
2020-01-01 Napagoda, M.; Gerstmeier, J.; Butschek, H.; De Soyza, S.; Pace, S.; Lorenz, S.; Qader, M.; Witharana, S.; Nagahawatte, A.; Wijayaratne, G.; Svatos, A.; Jayasinghe, L.; Koeberle, A.; Werz, O.
Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice
2021-01-01 Schädel, Patrick; Troisi, Fabiana; Czapka, Anna; Gebert, Nadja; Pace, Simona; Ori, Alessandro; Werz, Oliver
Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides
2021-01-01 Zhang, Kehong; Pace, Simona; Jordan, Paul M; Peltner, Lukas K; Weber, Alexander; Fischer, Dagmar; Hofstetter, Robert K; Chen, Xinchun; Werz, Oliver
Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation
2021-01-01 Neukirch, Konstantin; Alsabil, Khaled; Dinh, Chau-Phi; Bilancia, Rossella; Raasch, Martin; Ville, Alexia; Cerqua, Ida; Viault, Guillaume; Bréard, Dimitri; Pace, Simona; Temml, Veronika; Brunner, Elena; Jordan, Paul M; Marques, Marta C; Loeser, Konstantin; Gollowitzer, André; Permann, Stephan; Gerstmeier, Jana; Lorkowski, Stefan; Stuppner, Hermann; Garscha, Ulrike; Rodrigues, Tiago; Bernardes, Gonçalo J L; Schuster, Daniela; Séraphin, Denis; Richomme, Pascal; Rossi, Antonietta; Mosig, Alexander S; Roviezzo, Fiorentina; Werz, Oliver; Helesbeux, Jean-Jacques; Koeberle, Andreas
From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution
2021-01-01 Van Anh, Tran Thi; Mostafa, Alilou; Rao, Zhigang; Pace, Simona; Schwaiger, Stefan; Kretzer, Christian; Temml, Veronika; Giesel, Carsten; Jordan, Paul M.; Bilancia, Rossella; Weinigel, Christina; Rummler, Silke; Waltenberger, Birgit; Hung, Tran; Rossi, Antonietta; Stuppner, Hermann; Werz, Oliver; Koeberle, Andreas
The α-tocopherol-derived long-chain metabolite α-13′-COOH mediates endotoxin tolerance and modulates the inflammatory response via MAPK and NFκB pathways
2022-01-01 Schubert, Martin; Kluge, Stefan; Brunner, Elena; Pace, Simona; Birringer, Marc; Werz, Oliver; Lorkowski, Stefan
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Docosahexaenoic acid in the treatment of rheumatoid arthritis: A double-blind, placebo-controlled, randomized cross-over study with microalgae vs. sunflower oil | 1-gen-2018 | Dawczynski, C.; Dittrich, M.; Neumann, T.; Goetze, K.; Welzel, A.; Oelzner, P.; Volker, S.; Schaible, A. M.; Troisi, F.; Thomas, L.; Pace, S.; Koeberle, A.; Werz, O.; Schlattmann, P.; Lorkowski, S.; Jahreis, G. | |
| 5α-dihydrotestosterone abrogates sex bias in asthma like features in the mouse | 1-gen-2020 | Cerqua, I.; Terlizzi, M.; Bilancia, R.; Riemma, M. A.; Citi, V.; Martelli, A.; Pace, S.; Spaziano, G.; D'Agostino, B.; Werz, O.; Ialenti, A.; Sorrentino, R.; Cirino, G.; Rossi, A.; Roviezzo, F. | |
| Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution | 1-gen-2020 | Jordan, P. M.; Gerstmeier, J.; Pace, S.; Bilancia, R.; Rao, Z.; Borner, F.; Miek, L.; Gutierrez-Gutierrez, O.; Arakandy, V.; Rossi, A.; Ialenti, A.; Gonzalez-Estevez, C.; Loffler, B.; Tuchscherr, L.; Serhan, C. N.; Werz, O. | |
| Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammation | 1-gen-2018 | Bruno, F.; Errico, S.; Pace, S.; Nawrozkij, M. B.; Mkrtchyan, A. S.; Guida, F.; Maisto, R.; Olgac, A.; D'Amico, M.; Maione, S.; De Rosa, M.; Banoglu, E.; Werz, O.; Fiorentino, A.; Filosa, R. | |
| In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis | 1-gen-2014 | Rossi, A.; Pergola, C.; Pace, S.; Radmark, O.; Werz, O.; Sautebin, L. | |
| Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders | 1-gen-2020 | Brancaleone, V.; Dalli, J.; D'Emmanuele Di Villa Bianca, R.; Pace, S. | |
| Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions | 1-gen-2017 | Maione, F.; Cantone, V.; Pace, S.; Chini, M. G.; Bisio, A.; Romussi, G.; Pieretti, S.; Werz, O.; Koeberle, A.; Mascolo, N.; Bifulco, G. | |
| Sex-biased eicosanoid biology: Impact for sex differences in inflammation and consequences for pharmacotherapy | 1-gen-2017 | Pace, S.; Sautebin, L.; Werz, O. | |
| Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes | 1-gen-2020 | Rao, Z.; Jordan, P. M.; Wang, Y.; Menche, D.; Pace, S.; Gerstmeier, J.; Werz, O. | |
| Impact of Androgens on Inflammation-Related Lipid Mediator Biosynthesis in Innate Immune Cells | 1-gen-2020 | Pace, S.; Werz, O. | |
| Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold | 1-gen-2019 | Reale, A.; Brogi, S.; Chelini, A.; Paolino, M.; Di Capua, A.; Giuliani, G.; Cappelli, A.; Giorgi, G.; Chemi, G.; Grillo, A.; Valoti, M.; Sautebin, L.; Rossi, A.; Pace, S.; La Motta, C.; Di Cesare Mannelli, L.; Lucarini, E.; Ghelardini, C.; Anzini, M. | |
| Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation | 1-gen-2017 | Schieferdecker, S.; Konig, S.; Pace, S.; Werz, O.; Nett, M. | |
| Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy | 1-gen-2017 | Pergola, C.; Schubert, K.; Pace, S.; Ziereisen, J.; Nikels, F.; Scherer, O.; Huttel, S.; Zahler, S.; Vollmar, A. M.; Weinigel, C.; Rummler, S.; Muller, R.; Raasch, M.; Mosig, A.; Koeberle, A.; Werz, O. | |
| Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy | 1-gen-2019 | Gerstmeier, J.; Kretzer, C.; Di Micco, S.; Miek, L.; Butschek, H.; Cantone, V.; Bilancia, R.; Rizza, R.; Troisi, F.; Cardullo, N.; Tringali, C.; Ialenti, A.; Rossi, A.; Bifulco, G.; Werz, O.; Pace, S. | |
| The anti-inflammatory and antimicrobial potential of selected ethnomedicinal plants from Sri Lanka | 1-gen-2020 | Napagoda, M.; Gerstmeier, J.; Butschek, H.; De Soyza, S.; Pace, S.; Lorenz, S.; Qader, M.; Witharana, S.; Nagahawatte, A.; Wijayaratne, G.; Svatos, A.; Jayasinghe, L.; Koeberle, A.; Werz, O. | |
| Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice | 1-gen-2021 | Schädel, Patrick; Troisi, Fabiana; Czapka, Anna; Gebert, Nadja; Pace, Simona; Ori, Alessandro; Werz, Oliver | |
| Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides | 1-gen-2021 | Zhang, Kehong; Pace, Simona; Jordan, Paul M; Peltner, Lukas K; Weber, Alexander; Fischer, Dagmar; Hofstetter, Robert K; Chen, Xinchun; Werz, Oliver | |
| Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation | 1-gen-2021 | Neukirch, Konstantin; Alsabil, Khaled; Dinh, Chau-Phi; Bilancia, Rossella; Raasch, Martin; Ville, Alexia; Cerqua, Ida; Viault, Guillaume; Bréard, Dimitri; Pace, Simona; Temml, Veronika; Brunner, Elena; Jordan, Paul M; Marques, Marta C; Loeser, Konstantin; Gollowitzer, André; Permann, Stephan; Gerstmeier, Jana; Lorkowski, Stefan; Stuppner, Hermann; Garscha, Ulrike; Rodrigues, Tiago; Bernardes, Gonçalo J L; Schuster, Daniela; Séraphin, Denis; Richomme, Pascal; Rossi, Antonietta; Mosig, Alexander S; Roviezzo, Fiorentina; Werz, Oliver; Helesbeux, Jean-Jacques; Koeberle, Andreas | |
| From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution | 1-gen-2021 | Van Anh, Tran Thi; Mostafa, Alilou; Rao, Zhigang; Pace, Simona; Schwaiger, Stefan; Kretzer, Christian; Temml, Veronika; Giesel, Carsten; Jordan, Paul M.; Bilancia, Rossella; Weinigel, Christina; Rummler, Silke; Waltenberger, Birgit; Hung, Tran; Rossi, Antonietta; Stuppner, Hermann; Werz, Oliver; Koeberle, Andreas | |
| The α-tocopherol-derived long-chain metabolite α-13′-COOH mediates endotoxin tolerance and modulates the inflammatory response via MAPK and NFκB pathways | 1-gen-2022 | Schubert, Martin; Kluge, Stefan; Brunner, Elena; Pace, Simona; Birringer, Marc; Werz, Oliver; Lorkowski, Stefan |
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