IRISanRaf

Bio-Functional Investigation and AI-Driven Target Interaction Prediction of Chrono Control Penta as a Plant Multifunctional Dermo Cosmetic Peptide

Skin aging is influenced by both internal and external factors, resulting in wrinkles, decreased elasticity and irregular pigmentation. Hyaluronic acid (HA), a key component of the extracellular matrix, is essential for skin hydration and structural support. Peptides, short amino acid chains, have gained attention in cosmetics due to their multifunctional biological activities. This study explored the moisturizing and metal-chelating properties of Chrono Control Penta (S-Cannabis Sativa-penta...

The development of the EUropean Physical Activity Determinants framework for Adolescents (EU-PAD-A): a mixed-methods concept mapping study within the DE-PASS COST action

Background Most European adolescents do not meet recommended levels of physical activity (PA), increasing their risk of long-term health issues and contributing to the burden of non-communicable diseases. To address this public health challenge, there is a need for evidence-based, age-specific frameworks that identify the key determinants influencing PA behaviours during adolescence, a critical developmental stage for habit formation. Methods This study developed the EUropean Physical Activit...

Effects of a Multimodal Training Program for the Management of Urinary Incontinence and Physical Activity Levels on Symptom Perception and Urine Loss

Nano- and Microplastics in the Cardiovascular System: Current Insights and Biological Implications

Micro- and nanoplastics (MNPs) are ubiquitous environmental pollutants recognized as emerging and relevant risk factors for numerous human diseases, including cardiovascular diseases. MNPs enter the human body through ingestion, inhalation, and dermal penetration, and their toxicity varies according to size, shape, and chemical composition, most notably between microplastics (>1 µm) and nanoplastics (<1 µm), which differ in cellular uptake mechanisms and biodistribution. Recent evidence...