PACE, SIMONA
PACE, SIMONA
Dipartimento di Scienze Umane e Promozione della Qualità della Vita
5α-dihydrotestosterone abrogates sex bias in asthma like features in the mouse
2020-01-01 Cerqua, I.; Terlizzi, M.; Bilancia, R.; Riemma, M. A.; Citi, V.; Martelli, A.; Pace, S.; Spaziano, G.; D'Agostino, B.; Werz, O.; Ialenti, A.; Sorrentino, R.; Cirino, G.; Rossi, A.; Roviezzo, F.
A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity
2013-01-01 Battilocchio, C.; Poce, G.; Alfonso, S.; Porretta, G. C.; Consalvi, S.; Sautebin, L.; Pace, S.; Rossi, A.; Ghelardini, C.; Di Cesare Mannelli, L.; Schenone, S.; Giordani, A.; Di Francesco, L.; Patrignani, P.; Biava, M.
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors
2020-01-01 Lauro, G.; Terracciano, S.; Cantone, V.; Ruggiero, D.; Fischer, K.; Pace, S.; Werz, O.; Bruno, I.; Bifulco, G.
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors
2024-01-01 Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia
Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice
2021-01-01 Schädel, Patrick; Troisi, Fabiana; Czapka, Anna; Gebert, Nadja; Pace, Simona; Ori, Alessandro; Werz, Oliver
Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation
2023-01-01 Börner, Friedemann; Pace, Simona; Jordan, Paul M.; Gerstmeier, Jana; Gomez, Mario; Rossi, Antonietta; Gilbert, Nathaniel C.; Newcomer, Marcia E.; Werz, Oliver
Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males
2017-01-01 Pace, S.; Pergola, C.; Dehm, F.; Rossi, A.; Gerstmeier, J.; Troisi, F.; Pein, H.; Schaible, A. M.; Weinigel, C.; Rummler, S.; Northoff, H.; Laufer, S.; Maier, T. J.; Radmark, O.; Samuelsson, B.; Koeberle, A.; Sautebin, L.; Werz, O.
Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions
2017-01-01 Maione, F.; Cantone, V.; Pace, S.; Chini, M. G.; Bisio, A.; Romussi, G.; Pieretti, S.; Werz, O.; Koeberle, A.; Mascolo, N.; Bifulco, G.
Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators
2021-01-01 Pace, S.; Zhang, K.; Jordan, P. M.; Bilancia, R.; Wang, W.; Borner, F.; Hofstetter, R. K.; Potenza, M.; Kretzer, C.; Gerstmeier, J.; Fischer, D.; Lorkowski, S.; Gilbert, N. C.; Newcomer, M. E.; Rossi, A.; Chen, X.; Werz, O.
Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides
2021-01-01 Zhang, Kehong; Pace, Simona; Jordan, Paul M; Peltner, Lukas K; Weber, Alexander; Fischer, Dagmar; Hofstetter, Robert K; Chen, Xinchun; Werz, Oliver
Bioactivity and Mode of Action of Bacterial Tetramic Acids
2019-01-01 Klapper, M.; Paschold, A.; Zhang, S.; Weigel, C.; Dahse, H. -M.; Gotze, S.; Pace, S.; Konig, S.; Rao, Z.; Reimer, L.; Werz, O.; Stallforth, P.
BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly
2016-01-01 Garscha, U.; Voelker, S.; Pace, S.; Gerstmeier, J.; Emini, B.; Liening, S.; Rossi, A.; Weinigel, C.; Rummler, S.; Schubert, U. S.; Scriba, G. K. E.; Celikoglu, E.; Caliskan, B.; Banoglu, E.; Sautebin, L.; Werz, O.
Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators
2023-01-01 Peltner, Lukas K.; Gluthmann, Lars; Börner, Friedemann; Pace, Simona; Hoffstetter, Robert K.; Kretzer, Christian; Bilancia, Rosella; Pollastro, Federica; Koeberle, Andreas; Appendino, Giovanni; Rossi, Antonietta; Newcomer, Marcia E.; Gilbert, Nathaniel C.; Werz, Oliver; Jordan, Paul M.
Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis
2020-01-01 Werner, M.; Pace, S.; Czapka, A.; Jordan, P. M.; Gerstmeier, J.; Koeberle, A.; Werz, O.
Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes
2020-01-01 Rao, Z.; Jordan, P. M.; Wang, Y.; Menche, D.; Pace, S.; Gerstmeier, J.; Werz, O.
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization
2022-01-01 Cerqua, Ida; Musella, Simona; Peltner, Lukas Klaus; D'Avino, Danilo; Di Sarno, Veronica; Granato, Elisabetta; Vestuto, Vincenzo; Di Matteo, Rita; Pace, Simona; Ciaglia, Tania; Bilancia, Rossella; Smaldone, Gerardina; Di Matteo, Francesca; Di Micco, Simone; Bifulco, Giuseppe; Pepe, Giacomo; Basilicata, Manuela Giovanna; Rodriquez, Manuela; Gomez-Monterrey, Isabel M.; Campiglia, Pietro; Ostacolo, Carmine; Roviezzo, Fiorentina; Werz, Oliver; Rossi, Antonietta; Bertamino, Alessia
Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation
2018-01-01 Cheung, S. -Y.; Werner, M.; Esposito, L.; Troisi, F.; Cantone, V.; Liening, S.; Konig, S.; Gerstmeier, J.; Koeberle, A.; Bilancia, R.; Rizza, R.; Rossi, A.; Roviezzo, F.; Temml, V.; Schuster, D.; Stuppner, H.; Schubert-Zsilavecz, M.; Werz, O.; Hanke, T.; Pace, S.
Docosahexaenoic acid in the treatment of rheumatoid arthritis: A double-blind, placebo-controlled, randomized cross-over study with microalgae vs. sunflower oil
2018-01-01 Dawczynski, C.; Dittrich, M.; Neumann, T.; Goetze, K.; Welzel, A.; Oelzner, P.; Volker, S.; Schaible, A. M.; Troisi, F.; Thomas, L.; Pace, S.; Koeberle, A.; Werz, O.; Schlattmann, P.; Lorkowski, S.; Jahreis, G.
Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders
2020-01-01 Brancaleone, V.; Dalli, J.; D'Emmanuele Di Villa Bianca, R.; Pace, S.
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
2018-01-01 Pein, H.; Ville, A.; Pace, S.; Temml, V.; Garscha, U.; Raasch, M.; Alsabil, K.; Viault, G.; Dinh, C. -P.; Guilet, D.; Troisi, F.; Neukirch, K.; Konig, S.; Bilancia, R.; Waltenberger, B.; Stuppner, H.; Wallert, M.; Lorkowski, S.; Weinigel, C.; Rummler, S.; Birringer, M.; Roviezzo, F.; Sautebin, L.; Helesbeux, J. -J.; Seraphin, D.; Mosig, A. S.; Schuster, D.; Rossi, A.; Richomme, P.; Werz, O.; Koeberle, A.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 5α-dihydrotestosterone abrogates sex bias in asthma like features in the mouse | 1-gen-2020 | Cerqua, I.; Terlizzi, M.; Bilancia, R.; Riemma, M. A.; Citi, V.; Martelli, A.; Pace, S.; Spaziano, G.; D'Agostino, B.; Werz, O.; Ialenti, A.; Sorrentino, R.; Cirino, G.; Rossi, A.; Roviezzo, F. | |
| A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity | 1-gen-2013 | Battilocchio, C.; Poce, G.; Alfonso, S.; Porretta, G. C.; Consalvi, S.; Sautebin, L.; Pace, S.; Rossi, A.; Ghelardini, C.; Di Cesare Mannelli, L.; Schenone, S.; Giordani, A.; Di Francesco, L.; Patrignani, P.; Biava, M. | |
| A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors | 1-gen-2020 | Lauro, G.; Terracciano, S.; Cantone, V.; Ruggiero, D.; Fischer, K.; Pace, S.; Werz, O.; Bruno, I.; Bifulco, G. | |
| A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors | 1-gen-2024 | Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia | |
| Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice | 1-gen-2021 | Schädel, Patrick; Troisi, Fabiana; Czapka, Anna; Gebert, Nadja; Pace, Simona; Ori, Alessandro; Werz, Oliver | |
| Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation | 1-gen-2023 | Börner, Friedemann; Pace, Simona; Jordan, Paul M.; Gerstmeier, Jana; Gomez, Mario; Rossi, Antonietta; Gilbert, Nathaniel C.; Newcomer, Marcia E.; Werz, Oliver | |
| Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males | 1-gen-2017 | Pace, S.; Pergola, C.; Dehm, F.; Rossi, A.; Gerstmeier, J.; Troisi, F.; Pein, H.; Schaible, A. M.; Weinigel, C.; Rummler, S.; Northoff, H.; Laufer, S.; Maier, T. J.; Radmark, O.; Samuelsson, B.; Koeberle, A.; Sautebin, L.; Werz, O. | |
| Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions | 1-gen-2017 | Maione, F.; Cantone, V.; Pace, S.; Chini, M. G.; Bisio, A.; Romussi, G.; Pieretti, S.; Werz, O.; Koeberle, A.; Mascolo, N.; Bifulco, G. | |
| Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators | 1-gen-2021 | Pace, S.; Zhang, K.; Jordan, P. M.; Bilancia, R.; Wang, W.; Borner, F.; Hofstetter, R. K.; Potenza, M.; Kretzer, C.; Gerstmeier, J.; Fischer, D.; Lorkowski, S.; Gilbert, N. C.; Newcomer, M. E.; Rossi, A.; Chen, X.; Werz, O. | |
| Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides | 1-gen-2021 | Zhang, Kehong; Pace, Simona; Jordan, Paul M; Peltner, Lukas K; Weber, Alexander; Fischer, Dagmar; Hofstetter, Robert K; Chen, Xinchun; Werz, Oliver | |
| Bioactivity and Mode of Action of Bacterial Tetramic Acids | 1-gen-2019 | Klapper, M.; Paschold, A.; Zhang, S.; Weigel, C.; Dahse, H. -M.; Gotze, S.; Pace, S.; Konig, S.; Rao, Z.; Reimer, L.; Werz, O.; Stallforth, P. | |
| BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly | 1-gen-2016 | Garscha, U.; Voelker, S.; Pace, S.; Gerstmeier, J.; Emini, B.; Liening, S.; Rossi, A.; Weinigel, C.; Rummler, S.; Schubert, U. S.; Scriba, G. K. E.; Celikoglu, E.; Caliskan, B.; Banoglu, E.; Sautebin, L.; Werz, O. | |
| Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators | 1-gen-2023 | Peltner, Lukas K.; Gluthmann, Lars; Börner, Friedemann; Pace, Simona; Hoffstetter, Robert K.; Kretzer, Christian; Bilancia, Rosella; Pollastro, Federica; Koeberle, Andreas; Appendino, Giovanni; Rossi, Antonietta; Newcomer, Marcia E.; Gilbert, Nathaniel C.; Werz, Oliver; Jordan, Paul M. | |
| Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis | 1-gen-2020 | Werner, M.; Pace, S.; Czapka, A.; Jordan, P. M.; Gerstmeier, J.; Koeberle, A.; Werz, O. | |
| Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes | 1-gen-2020 | Rao, Z.; Jordan, P. M.; Wang, Y.; Menche, D.; Pace, S.; Gerstmeier, J.; Werz, O. | |
| Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization | 1-gen-2022 | Cerqua, Ida; Musella, Simona; Peltner, Lukas Klaus; D'Avino, Danilo; Di Sarno, Veronica; Granato, Elisabetta; Vestuto, Vincenzo; Di Matteo, Rita; Pace, Simona; Ciaglia, Tania; Bilancia, Rossella; Smaldone, Gerardina; Di Matteo, Francesca; Di Micco, Simone; Bifulco, Giuseppe; Pepe, Giacomo; Basilicata, Manuela Giovanna; Rodriquez, Manuela; Gomez-Monterrey, Isabel M.; Campiglia, Pietro; Ostacolo, Carmine; Roviezzo, Fiorentina; Werz, Oliver; Rossi, Antonietta; Bertamino, Alessia | |
| Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation | 1-gen-2018 | Cheung, S. -Y.; Werner, M.; Esposito, L.; Troisi, F.; Cantone, V.; Liening, S.; Konig, S.; Gerstmeier, J.; Koeberle, A.; Bilancia, R.; Rizza, R.; Rossi, A.; Roviezzo, F.; Temml, V.; Schuster, D.; Stuppner, H.; Schubert-Zsilavecz, M.; Werz, O.; Hanke, T.; Pace, S. | |
| Docosahexaenoic acid in the treatment of rheumatoid arthritis: A double-blind, placebo-controlled, randomized cross-over study with microalgae vs. sunflower oil | 1-gen-2018 | Dawczynski, C.; Dittrich, M.; Neumann, T.; Goetze, K.; Welzel, A.; Oelzner, P.; Volker, S.; Schaible, A. M.; Troisi, F.; Thomas, L.; Pace, S.; Koeberle, A.; Werz, O.; Schlattmann, P.; Lorkowski, S.; Jahreis, G. | |
| Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders | 1-gen-2020 | Brancaleone, V.; Dalli, J.; D'Emmanuele Di Villa Bianca, R.; Pace, S. | |
| Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase | 1-gen-2018 | Pein, H.; Ville, A.; Pace, S.; Temml, V.; Garscha, U.; Raasch, M.; Alsabil, K.; Viault, G.; Dinh, C. -P.; Guilet, D.; Troisi, F.; Neukirch, K.; Konig, S.; Bilancia, R.; Waltenberger, B.; Stuppner, H.; Wallert, M.; Lorkowski, S.; Weinigel, C.; Rummler, S.; Birringer, M.; Roviezzo, F.; Sautebin, L.; Helesbeux, J. -J.; Seraphin, D.; Mosig, A. S.; Schuster, D.; Rossi, A.; Richomme, P.; Werz, O.; Koeberle, A. |