Inherited susceptibility to lung cancer risk in never-smokers is poorly understood. The major reason for this gap in knowledge is that this disease is relatively uncommon (except in Asians), making it difficult to assemble an adequate study sample. In this study we conducted a genome-wide association study on the largest, to date, set of European-descent never-smokers with lung cancer.

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region

Bonassi, Stefano;
2019-01-01

Abstract

Inherited susceptibility to lung cancer risk in never-smokers is poorly understood. The major reason for this gap in knowledge is that this disease is relatively uncommon (except in Asians), making it difficult to assemble an adequate study sample. In this study we conducted a genome-wide association study on the largest, to date, set of European-descent never-smokers with lung cancer.
2019
Genetic susceptibility
Genome-wide association study
Lung cancer
Never smokers
Case-Control Studies
Europe
Female
Genetic Predisposition to Disease
Genetic Variation
Genome-Wide Association Study
Genotyping Techniques
Humans
Lung Neoplasms
Membrane Proteins
Middle Aged
Polymorphism, Single Nucleotide
Risk Factors
Telomerase
Chromosomes, Human, Pair 5
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12078/7626
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