Interferon beta (IFNb) is a safe first-line drug commonly used for relapsing-remitting (RR)-MS. Nevertheless, a considerable proportion of patients do not respond to IFNb treatment. Therefore, until now, a number of studies have investigated various markers that could predict the patients who would respond to IFNb therapy. The objective of this study was to identify reliable biomarkers to predict the efficacy of IFNb treatment in MS.

Cerebrospinal fluid inflammatory biomarkers predicting interferon-beta response in MS patients

Musella, Alessandra;Mandolesi, Georgia;
2020

Abstract

Interferon beta (IFNb) is a safe first-line drug commonly used for relapsing-remitting (RR)-MS. Nevertheless, a considerable proportion of patients do not respond to IFNb treatment. Therefore, until now, a number of studies have investigated various markers that could predict the patients who would respond to IFNb therapy. The objective of this study was to identify reliable biomarkers to predict the efficacy of IFNb treatment in MS.
NEDA-3
cerebrospinal fluid (CSF)
clinically isolated syndrome (CIS)
interferon beta (IFNb)
macrophage inflammatory protein (MIP)-1α
platelet-derived growth factor (PDGF)
relapsing-remitting (RR)-MS
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12078/7008
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