Background: Planar scintimammography is useful for characterizing breast lesions > 10 mm. Our aim was to evaluate Tc-99m sestamibi scintimammography with a hybrid (SPECT/CT) device for functional anatomical mapping (FAM). Patients and Methods: Three planar images and a chest SPECTICT were performed with a hybrid device in 53 patients with mammographically suspicious lesions. The final histopathological diagnosis was obtained after surgery. Results: The planar images were positive in 27 out of 37 carcinomas (sensitiviiy 73%) and the SPECTICT in 33 (sensitivity 89.2%). The sensitivity of planar imaging and SPECTICT was 42.9% and 71.4% in cancers <= 10 min, and 91.3%, and 100% in cancers > 10 mm, respectively. The specificity was 93.8% for both planar and SPECTICT imaging; accuracy was 79.2% for planar scans and 90.6% for SPECTICT FAM was useful in providing a precise anatomical localisation of the SPECT findings. Conclusion: SPECTICT scintimammography using a hybrid device is able to detect breast cancer, showing a sensitivity higher than that of planar images, especially for small cancers.
Scintimammography with a hybrid SPECT/CT imaging system
Danieli R;
2007-01-01
Abstract
Background: Planar scintimammography is useful for characterizing breast lesions > 10 mm. Our aim was to evaluate Tc-99m sestamibi scintimammography with a hybrid (SPECT/CT) device for functional anatomical mapping (FAM). Patients and Methods: Three planar images and a chest SPECTICT were performed with a hybrid device in 53 patients with mammographically suspicious lesions. The final histopathological diagnosis was obtained after surgery. Results: The planar images were positive in 27 out of 37 carcinomas (sensitiviiy 73%) and the SPECTICT in 33 (sensitivity 89.2%). The sensitivity of planar imaging and SPECTICT was 42.9% and 71.4% in cancers <= 10 min, and 91.3%, and 100% in cancers > 10 mm, respectively. The specificity was 93.8% for both planar and SPECTICT imaging; accuracy was 79.2% for planar scans and 90.6% for SPECTICT FAM was useful in providing a precise anatomical localisation of the SPECT findings. Conclusion: SPECTICT scintimammography using a hybrid device is able to detect breast cancer, showing a sensitivity higher than that of planar images, especially for small cancers.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
