Background: Planar scintimammography is useful for characterizing breast lesions > 10 mm. Our aim was to evaluate Tc-99m sestamibi scintimammography with a hybrid (SPECT/CT) device for functional anatomical mapping (FAM). Patients and Methods: Three planar images and a chest SPECTICT were performed with a hybrid device in 53 patients with mammographically suspicious lesions. The final histopathological diagnosis was obtained after surgery. Results: The planar images were positive in 27 out of 37 carcinomas (sensitiviiy 73%) and the SPECTICT in 33 (sensitivity 89.2%). The sensitivity of planar imaging and SPECTICT was 42.9% and 71.4% in cancers <= 10 min, and 91.3%, and 100% in cancers > 10 mm, respectively. The specificity was 93.8% for both planar and SPECTICT imaging; accuracy was 79.2% for planar scans and 90.6% for SPECTICT FAM was useful in providing a precise anatomical localisation of the SPECT findings. Conclusion: SPECTICT scintimammography using a hybrid device is able to detect breast cancer, showing a sensitivity higher than that of planar images, especially for small cancers.
Titolo: | Scintimammography with a hybrid SPECT/CT imaging system |
Autori: | |
Data di pubblicazione: | 2007 |
Rivista: | |
Abstract: | Background: Planar scintimammography is useful for characterizing breast lesions > 10 mm. Our aim was to evaluate Tc-99m sestamibi scintimammography with a hybrid (SPECT/CT) device for functional anatomical mapping (FAM). Patients and Methods: Three planar images and a chest SPECTICT were performed with a hybrid device in 53 patients with mammographically suspicious lesions. The final histopathological diagnosis was obtained after surgery. Results: The planar images were positive in 27 out of 37 carcinomas (sensitiviiy 73%) and the SPECTICT in 33 (sensitivity 89.2%). The sensitivity of planar imaging and SPECTICT was 42.9% and 71.4% in cancers <= 10 min, and 91.3%, and 100% in cancers > 10 mm, respectively. The specificity was 93.8% for both planar and SPECTICT imaging; accuracy was 79.2% for planar scans and 90.6% for SPECTICT FAM was useful in providing a precise anatomical localisation of the SPECT findings. Conclusion: SPECTICT scintimammography using a hybrid device is able to detect breast cancer, showing a sensitivity higher than that of planar images, especially for small cancers. |
Handle: | http://hdl.handle.net/20.500.12078/617 |
Appare nelle tipologie: | 1.1 Articolo in rivista |