This paper describes a synthesis of ALC-0315 by a sequence that more than doubles the overall yield relative to the published one, and that employs much cleaner reactions, thereby facilitating purifications to a considerable extent.
A Route to Lipid ALC-0315: a Key Component of a COVID-19 mRNA Vaccine
Cammarone S.;
2022-01-01
Abstract
This paper describes a synthesis of ALC-0315 by a sequence that more than doubles the overall yield relative to the published one, and that employs much cleaner reactions, thereby facilitating purifications to a considerable extent.File in questo prodotto:
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