Abstract: In eukaryotes mRNA transcripts are extensively processed by different post-transcriptional events such as alternative splicing and RNA editing in order to generate many different mRNAs from the same gene. Alternative splicing is a well recognized biological event for generating protein diversity, however RNA editing is less well known. The most common type of RNA editing in vertebrates and invertebrates is the conversion of specific adenosines to inosines within the RNA molecules by the ADAR family of enzymes. © 2008 Elsevier Ltd. All rights reserved.
RNA modifications and human diseases
Gallo A.
2008-01-01
Abstract
Abstract: In eukaryotes mRNA transcripts are extensively processed by different post-transcriptional events such as alternative splicing and RNA editing in order to generate many different mRNAs from the same gene. Alternative splicing is a well recognized biological event for generating protein diversity, however RNA editing is less well known. The most common type of RNA editing in vertebrates and invertebrates is the conversion of specific adenosines to inosines within the RNA molecules by the ADAR family of enzymes. © 2008 Elsevier Ltd. All rights reserved.File in questo prodotto:
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