Assessment of Frailty in Patients with Heart Failure: A New Heart Failure Frailty Score Developed by Delphi Consensus
2025-01-01 Vitale, Cristiana; Berthelot, Emmanuelle; Coats, Andrew J. S.; Loreena, Hill; Albert, Nancy M.; Tkaczyszyn, Michal; Adamopoulos, Stamatis; Anderson, Lisa; Anker, Markus S.; Anker, Stefan D.; Bell, Derek; Ben-Gal, Tuvia; Bistola, Vasiliki; Bozkurt, Biykem; Brooks, Poppy; Camafort, Miguel; Carrero, Juan Jesus; Chioncel, Ovidiu; Choi, Dong-Ju; Chung, Wook-Jin; Doehner, Wolfram; Fernández-Bergés, Daniel; Ferrari, Roberto; Fiuzat, Mona; Gomez-Mesa, Juan Esteban; Gustafsson, Finn; Jankowska, Ewa; Kang, Seok-Min; Kinugawa, Koichiro; Khunti, Kamlesh; Hobbs, F. D. Richard; Lee, Christopher; Lopatin, Yuri; Maddocks, Matthew; Maltese, Giuseppe; Marques-Sule, Elena; Matsue, Yuya; Miró, Òscar; Moura, Brenda; Piepoli, Massimo; Ponikowski, Piotr; Pulignano, Giovanni; Rakisheva, Amina; Ray, Robin; Sciacqua, Angela; Seferovic, Petar; Sentandreu-Mañó, Trinidad; Sze, Shirley; Sinclair, Alan; Strömberg, Anna; Theou, Olga; Tsutsui, Hiroyuki; Uchmanowicz, Izabella; Vidan, Maria Teresa; Volterrani, Maurizio; Von Haehling, Stephan; Yoo, Byungsu; Zhang, Jian; Zhang, Yuhui; Metra, Marco; Rosano, Giuseppe Massimo Claudio
Instruments to Measure Frailty in Patients with Heart Failure: a Narrative Review
2025-01-01 Vitale, Cristiana; Spoletini, Ilaria; Gianni, Walter; Rosano, Giuseppe Mc; Hage, Camilla
Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome
2019-01-01 Werner, M.; Jordan, P. M.; Romp, E.; Czapka, A.; Rao, Z.; Kretzer, C.; Koeberle, A.; Garscha, U.; Pace, S.; Claesson, H. -E.; Serhan, C. N.; Werz, O.; Gerstmeier, J.
The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo
2016-01-01 Schaible, A. M.; Filosa, R.; Krauth, V.; Temml, V.; Pace, S.; Garscha, U.; Liening, S.; Weinigel, C.; Rummler, S.; Schieferdecker, S.; Nett, M.; Peduto, A.; Collarile, S.; Scuotto, M.; Roviezzo, F.; Spaziano, G.; De Rosa, M.; Stuppner, H.; Schuster, D.; D'Agostino, B.; Werz, O.
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors
2020-01-01 Lauro, G.; Terracciano, S.; Cantone, V.; Ruggiero, D.; Fischer, K.; Pace, S.; Werz, O.; Bruno, I.; Bifulco, G.
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
2018-01-01 Pein, H.; Ville, A.; Pace, S.; Temml, V.; Garscha, U.; Raasch, M.; Alsabil, K.; Viault, G.; Dinh, C. -P.; Guilet, D.; Troisi, F.; Neukirch, K.; Konig, S.; Bilancia, R.; Waltenberger, B.; Stuppner, H.; Wallert, M.; Lorkowski, S.; Weinigel, C.; Rummler, S.; Birringer, M.; Roviezzo, F.; Sautebin, L.; Helesbeux, J. -J.; Seraphin, D.; Mosig, A. S.; Schuster, D.; Rossi, A.; Richomme, P.; Werz, O.; Koeberle, A.
BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly
2016-01-01 Garscha, U.; Voelker, S.; Pace, S.; Gerstmeier, J.; Emini, B.; Liening, S.; Rossi, A.; Weinigel, C.; Rummler, S.; Schubert, U. S.; Scriba, G. K. E.; Celikoglu, E.; Caliskan, B.; Banoglu, E.; Sautebin, L.; Werz, O.
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)
2014-01-01 Pergola, C.; Gerstmeier, J.; Monch, B.; Caliskan, B.; Luderer, S.; Weinigel, C.; Barz, D.; Maczewsky, J.; Pace, S.; Rossi, A.; Sautebin, L.; Banoglu, E.; Werz, O.
Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation
2018-01-01 Cheung, S. -Y.; Werner, M.; Esposito, L.; Troisi, F.; Cantone, V.; Liening, S.; Konig, S.; Gerstmeier, J.; Koeberle, A.; Bilancia, R.; Rizza, R.; Rossi, A.; Roviezzo, F.; Temml, V.; Schuster, D.; Stuppner, H.; Schubert-Zsilavecz, M.; Werz, O.; Hanke, T.; Pace, S.
Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction
2020-01-01 Gebert, N.; Cheng, C. -W.; Kirkpatrick, J. M.; Di Fraia, D.; Yun, J.; Schadel, P.; Pace, S.; Garside, G. B.; Werz, O.; Rudolph, K. L.; Jasper, H.; Yilmaz, O. H.; Ori, A.
Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males
2017-01-01 Pace, S.; Pergola, C.; Dehm, F.; Rossi, A.; Gerstmeier, J.; Troisi, F.; Pein, H.; Schaible, A. M.; Weinigel, C.; Rummler, S.; Northoff, H.; Laufer, S.; Maier, T. J.; Radmark, O.; Samuelsson, B.; Koeberle, A.; Sautebin, L.; Werz, O.
Bioactivity and Mode of Action of Bacterial Tetramic Acids
2019-01-01 Klapper, M.; Paschold, A.; Zhang, S.; Weigel, C.; Dahse, H. -M.; Gotze, S.; Pace, S.; Konig, S.; Rao, Z.; Reimer, L.; Werz, O.; Stallforth, P.
Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids
2015-01-01 Galuppo, M.; Rossi, A.; Giacoppo, S.; Pace, S.; Bramanti, P.; Sautebin, L.; Mazzon, E.
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity
2016-01-01 Di Capua, A.; Sticozzi, C.; Brogi, S.; Brindisi, M.; Cappelli, A.; Sautebin, L.; Rossi, A.; Pace, S.; Ghelardini, C.; Di Cesare Mannelli, L.; Valacchi, G.; Giorgi, G.; Giordani, A.; Poce, G.; Biava, M.; Anzini, M.
The chemopreventive action of bromelain, from pineapple stem (Ananas comosus L.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects
2014-01-01 Romano, B.; Fasolino, I.; Pagano, E.; Capasso, R.; Pace, S.; De Rosa, G.; Milic, N.; Orlando, P.; Izzo, A. A.; Borrelli, F.
A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity
2013-01-01 Battilocchio, C.; Poce, G.; Alfonso, S.; Porretta, G. C.; Consalvi, S.; Sautebin, L.; Pace, S.; Rossi, A.; Ghelardini, C.; Di Cesare Mannelli, L.; Schenone, S.; Giordani, A.; Di Francesco, L.; Patrignani, P.; Biava, M.
Humudifucol and Bioactive Prenylated Polyphenols from Hops (Humulus lupulus cv. "cascade")
2016-01-01 Forino, M.; Pace, S.; Chianese, G.; Santagostini, L.; Werner, M.; Weinigel, C.; Rummler, S.; Fico, G.; Werz, O.; Taglialatela-Scafati, O.
Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis
2020-01-01 Werner, M.; Pace, S.; Czapka, A.; Jordan, P. M.; Gerstmeier, J.; Koeberle, A.; Werz, O.
Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase
2017-01-01 Garscha, U.; Romp, E.; Pace, S.; Rossi, A.; Temml, V.; Schuster, D.; Konig, S.; Gerstmeier, J.; Liening, S.; Werner, M.; Atze, H.; Wittmann, S.; Weinigel, C.; Rummler, S.; Scriba, G. K.; Sautebin, L.; Werz, O.
SAR studies on curcumin's pro-inflammatory targets: Discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase
2014-01-01 Koeberle, A.; Munoz, E.; Appendino, G. B.; Minassi, A.; Pace, S.; Rossi, A.; Weinigel, C.; Barz, D.; Sautebin, L.; Caprioglio, D.; Collado, J. A.; Werz, O.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Assessment of Frailty in Patients with Heart Failure: A New Heart Failure Frailty Score Developed by Delphi Consensus | 1-gen-2025 | Vitale, Cristiana; Berthelot, Emmanuelle; Coats, Andrew J. S.; Loreena, Hill; Albert, Nancy M.; Tkaczyszyn, Michal; Adamopoulos, Stamatis; Anderson, Lisa; Anker, Markus S.; Anker, Stefan D.; Bell, Derek; Ben-Gal, Tuvia; Bistola, Vasiliki; Bozkurt, Biykem; Brooks, Poppy; Camafort, Miguel; Carrero, Juan Jesus; Chioncel, Ovidiu; Choi, Dong-Ju; Chung, Wook-Jin; Doehner, Wolfram; Fernández-Bergés, Daniel; Ferrari, Roberto; Fiuzat, Mona; Gomez-Mesa, Juan Esteban; Gustafsson, Finn; Jankowska, Ewa; Kang, Seok-Min; Kinugawa, Koichiro; Khunti, Kamlesh; Hobbs, F. D. Richard; Lee, Christopher; Lopatin, Yuri; Maddocks, Matthew; Maltese, Giuseppe; Marques-Sule, Elena; Matsue, Yuya; Miró, Òscar; Moura, Brenda; Piepoli, Massimo; Ponikowski, Piotr; Pulignano, Giovanni; Rakisheva, Amina; Ray, Robin; Sciacqua, Angela; Seferovic, Petar; Sentandreu-Mañó, Trinidad; Sze, Shirley; Sinclair, Alan; Strömberg, Anna; Theou, Olga; Tsutsui, Hiroyuki; Uchmanowicz, Izabella; Vidan, Maria Teresa; Volterrani, Maurizio; Von Haehling, Stephan; Yoo, Byungsu; Zhang, Jian; Zhang, Yuhui; Metra, Marco; Rosano, Giuseppe Massimo Claudio | |
| Instruments to Measure Frailty in Patients with Heart Failure: a Narrative Review | 1-gen-2025 | Vitale, Cristiana; Spoletini, Ilaria; Gianni, Walter; Rosano, Giuseppe Mc; Hage, Camilla | |
| Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome | 1-gen-2019 | Werner, M.; Jordan, P. M.; Romp, E.; Czapka, A.; Rao, Z.; Kretzer, C.; Koeberle, A.; Garscha, U.; Pace, S.; Claesson, H. -E.; Serhan, C. N.; Werz, O.; Gerstmeier, J. | |
| The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo | 1-gen-2016 | Schaible, A. M.; Filosa, R.; Krauth, V.; Temml, V.; Pace, S.; Garscha, U.; Liening, S.; Weinigel, C.; Rummler, S.; Schieferdecker, S.; Nett, M.; Peduto, A.; Collarile, S.; Scuotto, M.; Roviezzo, F.; Spaziano, G.; De Rosa, M.; Stuppner, H.; Schuster, D.; D'Agostino, B.; Werz, O. | |
| A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors | 1-gen-2020 | Lauro, G.; Terracciano, S.; Cantone, V.; Ruggiero, D.; Fischer, K.; Pace, S.; Werz, O.; Bruno, I.; Bifulco, G. | |
| Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase | 1-gen-2018 | Pein, H.; Ville, A.; Pace, S.; Temml, V.; Garscha, U.; Raasch, M.; Alsabil, K.; Viault, G.; Dinh, C. -P.; Guilet, D.; Troisi, F.; Neukirch, K.; Konig, S.; Bilancia, R.; Waltenberger, B.; Stuppner, H.; Wallert, M.; Lorkowski, S.; Weinigel, C.; Rummler, S.; Birringer, M.; Roviezzo, F.; Sautebin, L.; Helesbeux, J. -J.; Seraphin, D.; Mosig, A. S.; Schuster, D.; Rossi, A.; Richomme, P.; Werz, O.; Koeberle, A. | |
| BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly | 1-gen-2016 | Garscha, U.; Voelker, S.; Pace, S.; Gerstmeier, J.; Emini, B.; Liening, S.; Rossi, A.; Weinigel, C.; Rummler, S.; Schubert, U. S.; Scriba, G. K. E.; Celikoglu, E.; Caliskan, B.; Banoglu, E.; Sautebin, L.; Werz, O. | |
| The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP) | 1-gen-2014 | Pergola, C.; Gerstmeier, J.; Monch, B.; Caliskan, B.; Luderer, S.; Weinigel, C.; Barz, D.; Maczewsky, J.; Pace, S.; Rossi, A.; Sautebin, L.; Banoglu, E.; Werz, O. | |
| Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation | 1-gen-2018 | Cheung, S. -Y.; Werner, M.; Esposito, L.; Troisi, F.; Cantone, V.; Liening, S.; Konig, S.; Gerstmeier, J.; Koeberle, A.; Bilancia, R.; Rizza, R.; Rossi, A.; Roviezzo, F.; Temml, V.; Schuster, D.; Stuppner, H.; Schubert-Zsilavecz, M.; Werz, O.; Hanke, T.; Pace, S. | |
| Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction | 1-gen-2020 | Gebert, N.; Cheng, C. -W.; Kirkpatrick, J. M.; Di Fraia, D.; Yun, J.; Schadel, P.; Pace, S.; Garside, G. B.; Werz, O.; Rudolph, K. L.; Jasper, H.; Yilmaz, O. H.; Ori, A. | |
| Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males | 1-gen-2017 | Pace, S.; Pergola, C.; Dehm, F.; Rossi, A.; Gerstmeier, J.; Troisi, F.; Pein, H.; Schaible, A. M.; Weinigel, C.; Rummler, S.; Northoff, H.; Laufer, S.; Maier, T. J.; Radmark, O.; Samuelsson, B.; Koeberle, A.; Sautebin, L.; Werz, O. | |
| Bioactivity and Mode of Action of Bacterial Tetramic Acids | 1-gen-2019 | Klapper, M.; Paschold, A.; Zhang, S.; Weigel, C.; Dahse, H. -M.; Gotze, S.; Pace, S.; Konig, S.; Rao, Z.; Reimer, L.; Werz, O.; Stallforth, P. | |
| Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids | 1-gen-2015 | Galuppo, M.; Rossi, A.; Giacoppo, S.; Pace, S.; Bramanti, P.; Sautebin, L.; Mazzon, E. | |
| Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity | 1-gen-2016 | Di Capua, A.; Sticozzi, C.; Brogi, S.; Brindisi, M.; Cappelli, A.; Sautebin, L.; Rossi, A.; Pace, S.; Ghelardini, C.; Di Cesare Mannelli, L.; Valacchi, G.; Giorgi, G.; Giordani, A.; Poce, G.; Biava, M.; Anzini, M. | |
| The chemopreventive action of bromelain, from pineapple stem (Ananas comosus L.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects | 1-gen-2014 | Romano, B.; Fasolino, I.; Pagano, E.; Capasso, R.; Pace, S.; De Rosa, G.; Milic, N.; Orlando, P.; Izzo, A. A.; Borrelli, F. | |
| A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity | 1-gen-2013 | Battilocchio, C.; Poce, G.; Alfonso, S.; Porretta, G. C.; Consalvi, S.; Sautebin, L.; Pace, S.; Rossi, A.; Ghelardini, C.; Di Cesare Mannelli, L.; Schenone, S.; Giordani, A.; Di Francesco, L.; Patrignani, P.; Biava, M. | |
| Humudifucol and Bioactive Prenylated Polyphenols from Hops (Humulus lupulus cv. "cascade") | 1-gen-2016 | Forino, M.; Pace, S.; Chianese, G.; Santagostini, L.; Werner, M.; Weinigel, C.; Rummler, S.; Fico, G.; Werz, O.; Taglialatela-Scafati, O. | |
| Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis | 1-gen-2020 | Werner, M.; Pace, S.; Czapka, A.; Jordan, P. M.; Gerstmeier, J.; Koeberle, A.; Werz, O. | |
| Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase | 1-gen-2017 | Garscha, U.; Romp, E.; Pace, S.; Rossi, A.; Temml, V.; Schuster, D.; Konig, S.; Gerstmeier, J.; Liening, S.; Werner, M.; Atze, H.; Wittmann, S.; Weinigel, C.; Rummler, S.; Scriba, G. K.; Sautebin, L.; Werz, O. | |
| SAR studies on curcumin's pro-inflammatory targets: Discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase | 1-gen-2014 | Koeberle, A.; Munoz, E.; Appendino, G. B.; Minassi, A.; Pace, S.; Rossi, A.; Weinigel, C.; Barz, D.; Sautebin, L.; Caprioglio, D.; Collado, J. A.; Werz, O. |
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