Resorbable filter device could provide the critical protection against pulmonary embolism through the period of highest risk after major surgery or trauma, while avoiding the long-term disadvantages of currently available filtration devices. However, monitoring the integrity of these absorbable devices poses a challenge because of their inability to image using conventional imaging techniques, such as computed tomography (CT) and x-ray. Therefore, in this study, poly(p-dioxanone) [PPDO], a biodegradable polymer used as a filter device, is made radiopaque by coating with iodine-based contrast agents, 4-iodobenzoyl chloride (IBC) and 2,3,5-triiodobenzoyl acid (TIBA).
Development of radiopaque resorbable medical device
Tasciotti E;
2014-01-01
Abstract
Resorbable filter device could provide the critical protection against pulmonary embolism through the period of highest risk after major surgery or trauma, while avoiding the long-term disadvantages of currently available filtration devices. However, monitoring the integrity of these absorbable devices poses a challenge because of their inability to image using conventional imaging techniques, such as computed tomography (CT) and x-ray. Therefore, in this study, poly(p-dioxanone) [PPDO], a biodegradable polymer used as a filter device, is made radiopaque by coating with iodine-based contrast agents, 4-iodobenzoyl chloride (IBC) and 2,3,5-triiodobenzoyl acid (TIBA).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
