myo-inositol hexakisphosphate: Coordinative versatility of a natural product

myo-inositol phosphates are an important group of biomolecules that are present in the eukaryotic cells. The most abundant member of this family in nature is InsP6, usually called phytate. The importance of the interaction of InsP6 with cations has been recognized during the last years, and any attempt to know the function of this molecule in eukaryotic cells must include the fact that phytate will be strongly associated with simple inorganic and organic ammonium cations in solution. On the other hand, slightly soluble salts play an important role in phosphorous storage in plant kingdom and organophosphates found in soils. This review compiles the efforts during the last ten years to quantify and understand the interaction of InsP6 with different cations, either in solution or in the formation of solid phases. A coordination chemistry's view is used to describe the interaction of this versatile ligand with cations and organic amines, and how they can determine the self-assembly process in the formation of polynuclear complexes and solid phases.