IRISanRaf

Geometry and Art in Decorative Panels of Salerno Cathedral’s Floor

The paper dwells on an interesting Norman-era artistic episode that is in the San Matteo cathedral, in Salerno. Specifically, it is the mosaic floor of the church, stylistically attributable to the “Cosmatesque” art that, between the XII and XIII century, spread in the regions of central-southern Italy culturally influenced by the Byzantine world. After deepening the stylistic implications of the Cosmati, attention is paid to the geometries of the inlaid floor drawing, that define the aesthet...

Project Management and Graphic coordination

Basic mechanisms of plasticity and learning

The last century was characterized by a significant scientific effort aimed at unveiling the neurobiological basis of learning and memory. Thanks to the characterization of the mechanisms regulating the long-term changes of neuronal synaptic connections, it was possible to understand how specific neural networks shape themselves during the acquisition of memory traces or complex motor tasks. In this chapter, we will summarize the mechanisms underlying the main forms of synaptic plasticity tak...

Prevention of Adverse Metabolic Consequences of Adipocyte Dysfunction Using MR Antagonists

Adipocyte dysfunctions leading to obesity and associated cardiometabolic complications represent a strategic target to limit the spread of type 2 diabetes and obesity. The ligand-activated transcription factor mineralocorticoid receptor (MR) has been shown to regulate adipose tissue development and metabolism, playing an important role on adipogenesis, adipokine expression, and autophagy. Excessive activation of MR has been associated with dysfunctional adipose tissue and altered glucose home...