Background. Scintimammography with Tc-99m sestamibi has recently demonstrated a clinical usefulness in the evaluation of patients with breast lesions. The aim of this study was to assess the potential role of scintimammography using Tc99m tetrofosmin in the detection of breast cancer: Materials and Methods. Fifty-five patients (age range: 33-76 years) with suspicious breast abnormalities detected by mammography, and ten controls were examined. Dynamic images (1-20 min postinjection of the radiopharmaceutical) followed by three planar views were performed. Final diagnosis was achieved by hystology after surgery or excisional biopsy. Results. A total of 59 breast lesions were consider ed. The sensitivity of Tc-99m tetrofosmin scintimammography for detection of primary breast cancer was 93.1% (27/29) and the specificity was 93.3% (28/30). No focal uptake was observed in both breasts of the control population. Conclusions. Tc-99m tetrofosmin scintimammography has high diagnostic accuracy in detecting breast cancel and may have a clinical role as complement to conventional mammography.
Scintimammography with technetium-99m tetrofosmin in suspected breast cancer
Danieli R;
1997-01-01
Abstract
Background. Scintimammography with Tc-99m sestamibi has recently demonstrated a clinical usefulness in the evaluation of patients with breast lesions. The aim of this study was to assess the potential role of scintimammography using Tc99m tetrofosmin in the detection of breast cancer: Materials and Methods. Fifty-five patients (age range: 33-76 years) with suspicious breast abnormalities detected by mammography, and ten controls were examined. Dynamic images (1-20 min postinjection of the radiopharmaceutical) followed by three planar views were performed. Final diagnosis was achieved by hystology after surgery or excisional biopsy. Results. A total of 59 breast lesions were consider ed. The sensitivity of Tc-99m tetrofosmin scintimammography for detection of primary breast cancer was 93.1% (27/29) and the specificity was 93.3% (28/30). No focal uptake was observed in both breasts of the control population. Conclusions. Tc-99m tetrofosmin scintimammography has high diagnostic accuracy in detecting breast cancel and may have a clinical role as complement to conventional mammography.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
